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RIKEN Quantitative Biology Center (QBiC)

Cells can be thought of as complex systems in a dynamic equilibrium between multiple states that fluctuate stochastically. Our aim is to construct a numerical model that describes the common mechanisms regulating high-order function in complex biological systems. To understand the behavior of these systems, it is necessary to observe state transitions while at the same time quantitatively describing their dynamics. We are developing novel imaging systems that combine three major techniques to achieve this aim: 1) imaging systems which measure protein position, dynamics and the surrounding environment , 2) novel cell culture systems which can control and perturb the chemical/mechanical environment, and 3) custom designed biochemical/inorganic sensors that can visualize the status of the cell. The developed techniques will provide significant insight on the regulation of tissues, immunity, metabolism and aging by understanding the fundamental mechanisms that give rise to these disparate and complex systems.In turn, the information gained will significantly improve our ability to diagnose and treat diseases and advance the design of new medicines.




What'S NEW

February 1, 2017
Ms. Higashiguchi (Part-time staff) joined our team.
May 1, 2016
Ms. Tujita (Assistant) joined our team.
March 30, 2016
Ms. Rozanova (Ph.D student) joined our team.
January 18, 2016
Ms. Nakano (Part-time staff) joined our team.
May 1, 2015
Dr. Germond (Postdoctoral fellow) joined our team.
October 1, 2014
Dr. Mizushima (Postdoctoral fellow) joined our team.
June 12, 2014
Mr.Kaneshiro was awarded The Young Scientist Award for Presentation at the Annual Meeting of the Japan Society for Cell Biology.
April 1, 2014
Ms. Ohara (Part-time staff) joined our team.
October 1, 2013
Ms. David (Ph.D student) joined our team.
June 19, 2013
Mr.Morikawa was awarded The Young Scientists Award for the presentation at the Annual Meeting of the Japan Society for Cell Biology.
April 1, 2013
Dr.Okamoto (Postdoctoral fellow) joined our team.
December 21, 2012
The website is open.



























  Laboratory for Comprehensive
  Bioimaging
  RIKEN Quantitative Biology
  Center

  Team Leader:
  Tomonobu M. Watanabe


  Address:
  6-2-3, Furuedai, Suita,
  Osaka 565-0874,
  JAPAN
  Phone:+81-6-6155-0111
  FAX:+81-6-6155-0112