Welcome to Frey Initiative Research Unit (IRU, 国際主幹研究ユニット)
at the RIKEN Quantitative Biology Center



The Frey-IRU is a biosensors and bioelectronics laboratory at RIKEN that lab develops CMOS-based sensor devices targeting biological applications with primary focus in systems biology and systems neuroscience.


Bioelectronics

The lab focuses on bioelectronics, an emerging multidisciplinary research field at the interface between engineering, biology, nanotechnology and medicine. Next generation health-care devices, from lab-on-chip diagnostics, over neural interfaces to drug screening systems, will be powered by bioelectronics. Bioelectronics and biosensors have the potential to change how we interact and measure biological systems.

The lab’s core competences are CMOS-integrated microsensors and signal processing for biological applications. The lab is embedded in the Center of Developmental Biology, has access to biological expertise, state-of-the art bio facilities, MEMS facilities and IC-EDA tools.


CMOS-Based MEA

We design and use high-resolution microelectrode arrays (MEA) to interface with neuronal networks and advance the understanding of how neurons behave at a system level.

Biosensors

We build advanced biosensors for performing quantitative measurements of single cells and controlling the cellular state.